Antibacterial Activity of a New Cephalosporin, Cefotaxime
نویسندگان
چکیده
منابع مشابه
In vitro antimicrobial activity of cefotaxime, a new cephalosporin.
Cefotaxime, a new semisynthetic cephalosporin derivative, showed a broad spectrum of antibacterial activity against clinically isolated strains of gram-positive and gram-negative bacteria. This cephalosporin was slightly less active than cefazolin against Staphylococcus aureus but 4 to 300 times as active as carbenicillin against gram-negative organisms, including Pseudomonas aeruginosa, Pseudo...
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Sir: In recent years, a number of new parenteral cephalosporins with a broad spectrum of antibacterial activity and a high stability against various /Mactamases have been reported1}. Most of them have a 7j5-[(Z)-2-(2-aminothiazol-4-yl)-2-alkoxyiminoacetamido] side chain, such as ceftizoxime (CZX) and ceftazidime (CAZ). They show excellent activity against Gram-negative bacteria and moderate act...
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SM-1652 (sodium 7-[D(-)-alpha-(4-hydroxy-6-methylpyridine-3-carboxamido)-alpha-(4-hydroxyphenyl)acetamido]-3-[(1-methyl-1H-tetrazol-5-yl) thiomethyl]-3-cephem-4-carboxylate) is a new semisynthetic cephalosporin derivative with a broad spectrum of antibacterial activity. Its in vitro activity against gram-positive bacteria was comparable to that of cefazolin. SM-1652 exceeded cefazolin in potenc...
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Antibacterial activity of FK 749 against ampicillin-resistant clinical isolates of Escherichia coli was compared with those of other newly developed cephalosporins. FK 749 was the most active against strains possessing R-plasmids specifying ampicillin resistance and those whose resistance was chromosomally determined. The susceptibility of ampicillin-susceptible E. coli to FK 749 was not decrea...
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GODZESKI, C. W. (Eli Lilly & Co., Indianapolis, Ind.), GORDON BRIER, AND D. E. PAVEY. Cephalothin, a new cephalosporin with a broad antibacterial spectrum. I. In vitro studies employing the gradient plate technique. Appl. M\licrobiol. 11:122-127. 1963. Cephalothin is 7(thiophene-2-acetamido) cephalosporanic acid; it was prepared by N-acylation of the nucleus of cephalosporin C, 7-aminocephalosp...
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ژورنال
عنوان ژورنال: Journal of Applied Bacteriology
سال: 1980
ISSN: 0021-8847
DOI: 10.1111/j.1365-2672.1980.tb01051.x